Lehninger Principles of Biochemistry

Cover
This undergraduate textbook describes the structure and function of the major classes of cellular constituents, and explains the physical, chemical, and biological context in which each biomolecule, reaction, and pathway operates. The fourth edition adds a chapter on the regulation of metabolism, reflects recent advances, and incorporates new experimental methodologies and an expanded and redesigned treatment of reaction mechanisms. Annotation : 2004 Book News, Inc., Portland, OR (booknews.com).
 

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Nutzerbericht  - plaws595 - LibraryThing

I used this book in my undergraduate biochemistry course. I would have to say this is probably the best book to buy if you are looking for a good introduction on the many topics in biochemistry. The ... Vollständige Rezension lesen

Good book

Nutzerbericht  - biochemgirl - Overstock.com

Its a good book. Easy to navigate through the book. Chapters are clear. Vollständige Rezension lesen

Inhalt

The Foundations of Biochemistry
1
Hormonal Regulation and Integration
12
Biomolecules First Arose by Chemical Evolution
32
Functional Genomics Shows the Allocations of Genes
38
STRUCTURE AND CATALYSIS
45
Entropy Increases as Crystalline Substances Dissolve
51
An Osmotic Event
59
Buffers Are Mixtures of Weak Acids and Their Conjugate
66
The Citric Acid Cycle Is Regulated at Its Three Exergonic
622
of Urea
656
Glutamine Transports Ammonia in the Bloodstream
662
The Citric Acid and Urea Cycles Can Be Linked
668
Six Amino Acids Are Degraded to Pyruvate
674
Five Amino Acids Are Converted to aketoglutarate
681
The B Oxidation of Saturated Fatty Acids Has Four Basic
688
The Proton Gradient Drives the Release of ATP from
709

Protein Sequences Can Elucidate the History of Life
107
Box 42 Permanent Waving Is Biochemical Engineering
127
Globular Proteins Have a variety of Tertiary Structures
134
Protein Motifs Are the Basis for Protein Structural
141
Amino Acid Sequence Determines Tertiary Structure
148
Protein Function
157
Hemoglobin Subunits Are Structurally Similar
163
Hemoglobin Also Transports H+ and CO2
170
Self Is Distinguished from Nonself by the Display of Peptides
176
Actin Myosin and Molecular Motors
182
The Relationship between Substrate Concentration
203
Carbohydrates and Glycobiology
238
Monosaccharides Are Reducing Agents
244
Steric Factors and Hydrogen Bonding Influence
250
Proteoglycans Are GlycosaminoglycanContaining
256
Lectins Are Proteins That Read the Sugar Code and Mediate
262
on Chromosome Structure and Gene Expression
333
Some Bases of DNA Are Methylated 296
343
Sphingolipids at Cell Surfaces Are Sites of Biological
353
Steroid Hormones Carry Messages between Tissues
359
Adsorption Chromatography Separates Lipids of Different
365
Biological Membranes and Transport 369
416
Receptor Guanylyl Cyclases Generate the Second Messenger
433
Calcium Is a Second Messenger in Many Signal
442
Membrane Rafts and Caveolae May Segregate Signaling
451
Light Triggers Conformational Changes in the Receptor
457
Disruption of GProtein Signaling Causes Disease
464
CDKs Regulate Cell Division by Phosphorylating Critical
470
Glycolysis Gluconeogenesis and
521
The Payoff Phase of Glycolysis Produces ATP
529
Dietary Polysaccharides and Disaccharides Undergo
535
Fermentation
538
Conversion of Pyruvate to Phosphoenolpyruvate Requires
544
The Oxidative Phase Produces Pentose Phosphates
550
Glycogen Breakdown Is Catalyzed by Glycogen
597
A Symmetrical Molecule That Reacts
614
HARVESTING LIGHT ENERGY
723
Principles of Bioenergetics 489
745
Bacteria
751
The Salvage of Phosphoglycolate Is Costly
767
Cell
780
The Fatty Acid Synthase Reactions Are Repeated to Form Nitrogen Is Fixed by Enzymes of the Nitrogenase
834
Acetate Is Shuttled out of Mitochondria as Citrate 794 Several Classes of Reactions Play Special Roles in
840
Cyclooxygenase Isozymes and Tryptophan Phenylalanine and Tyrosine
849
Phospholipid Synthesis in E coli Employs CDP Aromatic Amino Acids Are Precursors of Many Plant
859
Carbamoyl Phosphate
867
Cholesterol Biosynthesis Is Regulated at Several Levels 825 Degradation of Purines and Pyrimidines Produces Uric Acid
873
and Related Molecules 833 23 Hormonal Regulation and Integration
881
The Discovery and Purification of Hormones Require
882
Hormone Release Is Regulated by a Hierarchy of Neuronal
889
Adipose Tissue Stores and Supplies Fatty Acids
897
Insulin Counters High Blood Glucose
904
Leptin Stimulates Production of Anorexigenic Peptide
912
HII INFORMATION PATHWAYS
921
Biological Energy Transformations Obey the Laws
922
DNA Metabolism
948
RNA Metabolism
995
RNA Polymerase II Requires Many Other Protein Factors
1003
RNA Catalyzes the Splicing of Introns
1009
RNA Enzymes Are the Catalysts of Some Events in
1017
Some Retroviruses Cause Cancer and AIDS
1023
Box 263 The SELEX Method for Generating RNA polymers with
1030
Protein Metabolism
1034
Regulation of Gene Expression
1081
Translational
1092
Cells Require Sources of Free Energy 491
1120
Protein Biosynthesis Takes Place in Five Stages 1044
1120
Nonsense
1120
Appendix A Common Abbreviations in the Biochemical Research
1120
Literature
1-1
Amino Acids Share Common Structural Features 76
1-2
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